Ultrasound-Mediated
Nonviral Genetic
Medicine
Who We Are
Bringing the future of genetic medicine to patients.
Using nonviral, ultrasound mediated delivery (UMD), we are developing a proprietary, non-invasive approach which enables broad, highly targeted biodistribution, delivery of diverse genetic payloads without size restriction, in a redosable manner designed to be safe, well tolerated and cost-effective.
Using Ultrasound-Mediated Delivery
SonoThera is developing a proprietary, nonviral, non-invasive approach which enables:
Broad, Highly Targeted Biodistribution
Our proprietary ultrasound profiles enable highly targeted biodistribution to nearly any organ in the body without unwanted off-target delivery.
Delivery of Diverse Genetic Medicines Without Size Restriction
Our proprietary technology enables delivery of DNA and/or RNA constructs of unlimited size, expressing full-length transgenic proteins; gene editors, siRNAs and ASOs.
In a Redosable Manner
Our novel technology is redosable, maintaining stable, personalized therapeutic gene expression levels over time.
Designed to be Safe, Well-Tolerated and Cost-Effective
Our technology avoids the immunogenicity and material-related toxicity of nonviral and viral vectors (AAVs and LNPs).
Our Investors
Newsroom
Platform Overview
Ultrasound-Mediated Gene Delivery
We have developed a proprietary gene delivery technology, which enables us to deliver genetic material to a chosen site using ultrasound and ultrasound enhancing agents (UAEs), more commonly known as microbubbles. Learn More
Unlimited Genetic Payload
(any nucleic acid format of unlimited size)
IV Injection of UEA
& nucleic acid payload
Transcutaenous delivery
of proprietary acoustic profile
Ultrasound energy drives vascular escape & tissue penetration of UEAs & payloads
Transient cell membrane pore formation
Nuclear Entry & Expression
Genetic medicine holds extraordinary promise, yet too many patients remain out of reach due to limitations in delivery biodistribution, safety, immunogenicity, durability, and cost. It’s time for a paradigm shift. SonoThera’s proprietary approach is designed to overcome these barriers and bring genetic medicine to more people who need it.
Build the future of genetic medicine.
Our team of scientists are tackling the hardest problems in biology and medicine. Join us on our journey to shape genetic medicine.