Published Research

Successful proof of concept studies and reviews on the topic of sonoporation and gene delivery.

Castle, Jason et al. “Sonoporation for Augmenting Chemotherapy of Pancreatic Ductal Adenocarcinoma.” Methods in molecular biology 2059 (2020): 191-205”

Sirsi, Shashank R. and Mark Andrew Borden. “Advances in Ultrasound Mediated Gene Therapy Using Microbubble Contrast Agents.” Theranostics 2 (2012): 1208 – 1222.

Castle, Jason et al. “Ultrasound-mediated targeted drug delivery: recent success and remaining challenges.” American journal of physiology. Heart and circulatory physiology 304 3 (2013): H350-7.

Castle, Jason and Steven B. Feinstein. “Ultrasound-directed, site-specific gene delivery.” Methods in molecular biology 1141 (2014): 67-76.

Castle, Jason et al. “Therapeutic ultrasound: Increased HDL-Cholesterol following infusions of acoustic microspheres and apolipoprotein A-I plasmids.” Atherosclerosis 241 1 (2015): 92-9.

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